\[ \int (d+e x)^{5/2} \left (a d e+\left (c d^2+a e^2\right ) x+c d e x^2\right )^{3/2} \, dx \]
Optimal antiderivative \[ \frac {256 \left (-a \,e^{2}+c \,d^{2}\right )^{4} \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {5}{2}}}{15015 c^{5} d^{5} \left (e x +d \right )^{\frac {5}{2}}}+\frac {128 \left (-a \,e^{2}+c \,d^{2}\right )^{3} \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {5}{2}}}{3003 c^{4} d^{4} \left (e x +d \right )^{\frac {3}{2}}}+\frac {2 \left (e x +d \right )^{\frac {3}{2}} \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {5}{2}}}{13 c d}+\frac {32 \left (-a \,e^{2}+c \,d^{2}\right )^{2} \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {5}{2}}}{429 c^{3} d^{3} \sqrt {e x +d}}+\frac {16 \left (-a \,e^{2}+c \,d^{2}\right ) \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {5}{2}} \sqrt {e x +d}}{143 c^{2} d^{2}} \]
command
integrate((e*x+d)^(5/2)*(a*d*e+(a*e^2+c*d^2)*x+c*d*e*x^2)^(3/2),x, algorithm="giac")
Giac 1.9.0-11 via sagemath 9.6 output
\[ \text {output too large to display} \]
Giac 1.7.0 via sagemath 9.3 output \[ \int {\left (c d e x^{2} + a d e + {\left (c d^{2} + a e^{2}\right )} x\right )}^{\frac {3}{2}} {\left (e x + d\right )}^{\frac {5}{2}}\,{d x} \]_______________________________________________________