\[ \int (d+e x)^{5/2} \sqrt {a d e+\left (c d^2+a e^2\right ) x+c d e x^2} \, dx \]
Optimal antiderivative \[ \frac {32 \left (-a \,e^{2}+c \,d^{2}\right )^{3} \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {3}{2}}}{315 c^{4} d^{4} \left (e x +d \right )^{\frac {3}{2}}}+\frac {2 \left (e x +d \right )^{\frac {3}{2}} \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {3}{2}}}{9 c d}+\frac {16 \left (-a \,e^{2}+c \,d^{2}\right )^{2} \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {3}{2}}}{105 c^{3} d^{3} \sqrt {e x +d}}+\frac {4 \left (-a \,e^{2}+c \,d^{2}\right ) \left (a d e +\left (a \,e^{2}+c \,d^{2}\right ) x +c d e \,x^{2}\right )^{\frac {3}{2}} \sqrt {e x +d}}{21 c^{2} d^{2}} \]
command
integrate((e*x+d)^(5/2)*(a*d*e+(a*e^2+c*d^2)*x+c*d*e*x^2)^(1/2),x, algorithm="giac")
Giac 1.9.0-11 via sagemath 9.6 output
\[ \frac {2}{315} \, {\left (105 \, d^{3} {\left (\frac {{\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {3}{2}} e^{\left (-1\right )}}{c d} + \frac {\sqrt {-c d^{2} e + a e^{3}} c d^{2} - \sqrt {-c d^{2} e + a e^{3}} a e^{2}}{c d}\right )} e^{\left (-1\right )} - 63 \, d^{2} {\left (\frac {{\left (5 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {3}{2}} a e^{3} - 3 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {5}{2}}\right )} e^{\left (-2\right )}}{c^{2} d^{2}} + \frac {3 \, \sqrt {-c d^{2} e + a e^{3}} c^{2} d^{4} - \sqrt {-c d^{2} e + a e^{3}} a c d^{2} e^{2} - 2 \, \sqrt {-c d^{2} e + a e^{3}} a^{2} e^{4}}{c^{2} d^{2}}\right )} e^{\left (-1\right )} + 9 \, d {\left (\frac {{\left (15 \, \sqrt {-c d^{2} e + a e^{3}} c^{3} d^{6} - 3 \, \sqrt {-c d^{2} e + a e^{3}} a c^{2} d^{4} e^{2} - 4 \, \sqrt {-c d^{2} e + a e^{3}} a^{2} c d^{2} e^{4} - 8 \, \sqrt {-c d^{2} e + a e^{3}} a^{3} e^{6}\right )} e^{\left (-2\right )}}{c^{3} d^{3}} + \frac {{\left (35 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {3}{2}} a^{2} e^{6} - 42 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {5}{2}} a e^{3} + 15 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {7}{2}}\right )} e^{\left (-5\right )}}{c^{3} d^{3}}\right )} e - {\left (\frac {{\left (35 \, \sqrt {-c d^{2} e + a e^{3}} c^{4} d^{8} - 5 \, \sqrt {-c d^{2} e + a e^{3}} a c^{3} d^{6} e^{2} - 6 \, \sqrt {-c d^{2} e + a e^{3}} a^{2} c^{2} d^{4} e^{4} - 8 \, \sqrt {-c d^{2} e + a e^{3}} a^{3} c d^{2} e^{6} - 16 \, \sqrt {-c d^{2} e + a e^{3}} a^{4} e^{8}\right )} e^{\left (-3\right )}}{c^{4} d^{4}} + \frac {{\left (105 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {3}{2}} a^{3} e^{9} - 189 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {5}{2}} a^{2} e^{6} + 135 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {7}{2}} a e^{3} - 35 \, {\left ({\left (x e + d\right )} c d e - c d^{2} e + a e^{3}\right )}^{\frac {9}{2}}\right )} e^{\left (-7\right )}}{c^{4} d^{4}}\right )} e^{2}\right )} e^{\left (-1\right )} \]
Giac 1.7.0 via sagemath 9.3 output
\[ \int \sqrt {c d e x^{2} + a d e + {\left (c d^{2} + a e^{2}\right )} x} {\left (e x + d\right )}^{\frac {5}{2}}\,{d x} \]________________________________________________________________________________________